Comprehensive geriatric assessment and drug burden in elderly chronic kidney disease patients

Abstract Objectives Chronic kidney disease (CKD) is a condition characterized by atherosclerosis, cognitive impairment, physical limitations, biochemical abnormalities, and vascular aging. The proportion of those with diagnosis CKD in the older increasing. With comprehensive geriatric assessment, it could be possible to detect disorders that are related biological aim evaluate syndromes like frailty, dysfunction, malnutrition, polypharmacy an aged population pre-dialytic (stages 3a–5), investigate relations features anticholinergic drug burden (ADB). Methods One hundred fifty-six patients 60 164 healthy controls were included study. Geriatric parameters used for evaluation groups were, Clinical Frailty Index; Charlson Comorbidity Montreal Cognitive Assessment Mini Nutritional Assessment-short form. Besides, ADB defined 3 scales Anticholinergic Burden Classification (ABC), Chew’s scale, Drug Index recorded. Results Despite being younger, had higher comorbidity frailty scores than controls. Patients similar nutritional status, function test results. was important predictor eGFR. ABC score group scale. Conclusions more prevalent expected CKD. In addition, may form causal links one other lead increased mortality rates especially frailty. Therefore, assessment appropriate recommended patients.